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Ecosave: against which kinds of poison?

ECOSAVE's operation is based on the principle of the electric discharges that is effective against haemotoxic venom and not against neurotoxic venom. IMPORTANT: the validity of this principle has been demonstrated in real circumstances; it has not been applied on all the poisons against which it could theoretically be effective, (above all in the cases of the rarest animals), because of the experimentation difficulties and the impossibility of carrying out laboratory tests in Europe (that cannot be reliable if carried out with lyophilized venom).

In the following paragraphs, we will try to indicate in a simplified way, the animals that produce a haemotoxic kind of venom and the ones that produce a neurotoxic kind of venom.
Because of the complexity of this matter, the lack of clarity and the non-completeness of the knowledge at our disposal today, above all as far as the rarest species are concerned, the reported information is given by way of simple indication and does not want to be exhaustive at all.



SNAKES


Of all the snakes, just a part of them injects venom when it bites, and in general all of them bite only when they are bothered or feel to be in danger.
Snakes' venom is composed of a combination of protein molecules and toxins that act differently depending on their composition. There are mainly two different kinds of venom, classified as per the produced effects: neurotoxic poisons and haemotoxic venom. The neurotoxins, that prevail in the neurotoxic venom, act on the nervous system, provoking the interruption of the nerve impulse's transmission, with the temporary numbness of the affected area and intense pain, and on the respiratory system, causing respiratory failure. If the venom is particularly aggressive and in proportional quantities if compared to the victim's size, it can lead to paralysis, with the consequent cardiac arrest or to asphyxia and consequently to death.

The haemotoxic venom is mostly composed of haemotoxins, that act on the cardiovascular system, on the hemocoagulation system and on the red blood cells, destroying them and triggering a chain reaction in the affected body, culminating, in the most severe cases, in the blood coagulation or in internal bleeding which lead, in most cases, to death.
The venom produced by the snakes' venomous glands is generally of both kinds, but normally just one type is predominant, and it is starting from this that the snake is classified as neurotoxic venom snakes or haemotoxic venom snakes.
Among the snakes that inject haemotoxic venom we can include:
- Viperids (European and other Continents' vipers)
- Crotalids (the American rattlesnake).

On the contrary, among the snakes that inject neurotoxic venom we can enumerate:
- Cobra
- Mamba
- Coral Snakes
- Taipan
- Sea-snakes.

See list

Warning
Ecosave is effective against snakes bites belonging to the first group, since it acts on the haemotoxic kinds of poison; on the contrary it is not effective on the neurotoxic kinds of poison.



INSECTS

Vespids (wasps, bumble-bees) and Apids (bees)

In several Apids' poisons (above all in our country's Apis mellifera) and in Vespids' poisons, (above all, in Italy, the Vespa crabro or bumble-bee, Polistes gallicus or paper wasp, Vespula germanica or German wasp, Vespula vulgaris or common wasp, and other wasps of the Vespula kind), there are complex toxic substances, that in normosensitive individuals, provoke local symptoms that can persist for many hours, for example an intense pain and an erythema-oedematous reaction on the affected part, which are effectively treatable with ECOSAVE. Generally, a normosensitive person can tolerate many stings, without irreversible damages.
On the contrary, hypersensitive and allergic subjects can develop more severe manifestations, that can vary from acute urticaria to oedema (which are usually combined), to bronchial asthma until the anaphylactic shock with sudden coma and cardiac-respiratory arrest. In these cases, ECOSAVE can decelerate the quick progression of the toxic effects, but it cannot prevent them, and the therapeutic intervention remains crucial. In an allergic person, one sting only can cause an anaphylactic reaction with a fatal outcome.


ARACHNIDAN

Spiders

Almost all the spiders are venomous, but most of them have very small and brittle teeth to penetrate into the skin, and their venom is not strong enough, or the quantities that they can inject is too scarce to endanger man (obviously with the due exceptions).
The most venomous spiders belong to the varieties Latrodectus, Loxosceles and Lycosa (secondarily) that also live in Europe.
The species that are able to sting, eject from the aculeate end of their pincers, substances having a mainly hemolytic action that paralyze or kill their preys.

Usually, the most serious spider bites are the ones that inject the neurotoxic principles (as for the black widow; this case of poisoning is called lactrodectism) and necrotizing or haemotoxic principles (brown spiders, violin spiders and some house spiders; in this case it is called loxoscelism).

ECOSAVE is based on a principle that can be generally applied to neutralize the "house" spiders' venom, for example the house-spider or the tarantula, and against loxoscelism; it could also be used in case of lactrodectism to reduce the local symptoms of pain, stinging, swelling, flush and possible necrosis on the affected area, but not against the most extended neurotoxic manifestations that require medical help and a suitable antibiotic therapy.
See list


Scorpions
Most of the scorpions, especially in Italy, are relatively harmless, since they can sting but they are not dangerous; as a matter of fact their stings generally cause just localized pain, itching, stinging and swelling; in case the regional hyperadenosis they can cause the skin temperature's increase and the sensitivity around the wound. In most cases, the effects of their sting are comparable to the ones of a wasp's sting in a normosensitive subject.
Some species belonging to the variety of Centruroides, Androctonus, Tityus, Leinus and Buthus, common above all in the Southern regions of North, Central and Southern America, in Africa, in the Middle East and in Asia, clearly have more toxic venoms if compared to many other species. Their sting can cause more severe manifestations, as the outbreak of inflammatory reactions or of necrotic-hemorrhagic lesions, until cardiotoxic effects in the worst cases, sometimes being so serious that they can result to be lethal.
Anyway, the effects depend on the kind and on the dimensions of the scorpion, on the affected subject's reactivity and on his weight, that influences the concentration of the venom in his organism.

ECOSAVE is based on the principle that is generally applicable to reduce or cure the local symptomatology (stinging and swelling) in the greatest part of the a bites. Nevertheless, ECOSAVE's efficacy is ensured only as a first aid instrument, in case of hypersensitive people and in case of development of a more complex systemic symptomatology.


MARINE ANIMALS

Coelenterate (jellyfishes, corals, sea anemones and hydroids)

They all have very well differentiated stinging apparatuses, the nematocyst, that penetrates the human skin. The immediate consequences are stinging, itching, flush and swelling. The most severe clinical systemic manifestations, that depend on the species the subject has got in contact with and on his sensitivity, generally include weakness, nausea, headache, muscular aches and spasms, lachrymation and running nose, increase in transpiration, heart-beat's alteration and thoracic pleura aches.

ATTENTION: in the most dangerous species' venom, the neurotoxic components are predominant: ECOSAVE is then not effective.

Jellyfish. The jellyfishes' urtications are all due to the nematocysts's discharges, that is made of capsular filaceous structures containing substances having an urticant and/or toxic action, ejected by specialized cells called cnidoblasts (cnidos means “stinging nettle”) that can mainly be found on the tentacles.
The contact with the tentacles of the jellyfishes that live in the Mediterranean Sea leads to urticary lesions that provoke more or less intense stingings.
In some species of jellyfishes, as the Carukia barnesi and the Chironex fleckeri, both inhabitants of the Australian Seas, the so-called “sea wasp or box jellyfish” Chiropsalmus quadrigatu, in the Pacific Ocean between Australia and the Philippines, or the “Portuguese Man-of-war” Physalia Physalis, in the tropical and subtropical waters, the greater toxicity of the nematocysts can provoke a more severe systemic symptomatology, that sometimes can lead to the death of the affected person. Their venom is a mixture of different toxins that can affect, in accordance with the kind, the nervous system, the muscular one and the red blood cells also provoking cell necrosis.


ECOSAVE is based on the principle that can be used to relieve the local symptomatology (stinging, itching, flush) provoked by the urtications, also severe, of jellyfishes living in our Seas; it is not effective against the proteic neurotoxic compositions of tropical jellyfishes.

Fishes e Shellfishes
Different species of fishes have stings or spines connected to glands producing stinging substances that, if injected into the human skin, are responsible for intense pain, oedema and sometimes limited necrosis.

Among the animals that inject a haemotoxic kind of venom, against which ECOSAVE is effective, the most common is the greater weever.

On the contrary, among the fishes that produce a venom that can induce a neurotoxic kind of general symptomatology, sometimes with convulsions and shock, there are some fishes common in the Mediterranean Sea (ray, weever-fish, cat fish, long-spined bullhead, etc.) and many inhabitants of the tropical seas, as the stonefish (Synanceja Horrida) and the scorpionfish (Pterois Volitans) or, among the shellfishes, the Conus geographus that colonizes the tropical barrier reefs, and the Octopus maculosus, common in the Australian seas.


 
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